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  • Genetic variation in mother-child acute seroconverter pairs from Zambia

    Objective: To characterize the envelope (Env) glycoprotein of HIV-1 in mother-infant pairs (MIP) that underwent near simultaneous or acute-phase seroconversion, we examined the Env sequence of the transmitted viruses and compare viral evolution within the pair. Design: Three MIP from a Zambian cohort that seroconverted at the same sampling time were identified and followed longitudinally. Methods: The V1-V5 region of the HIV-1 Env gene was sequenced for each sample collected. Phylogenetic and population genetics analyses were carried out to subtype the viruses, estimate relationships among viral genotypes, and compare molecular evolution between the viral populations. Results: Genetic analyses demonstrated a close intrapair relationship between viral sequences from each MIP. Transmission involved several closely related viral genotypes and did not result in a reduction in viral diversity. Amino acid changes were not evenly distributed along Env V1-V5 but concentrated in concordant areas within each MIP. Several positions under positive selection were shared between the MIP viruses. Interestingly, selective pressure on the virus was higher in the infants than in the mothers.
  • Preventing mother-to-child transmission of HIV in rural Zambia

    For the past eight months, 34-year-old Regina, a mother in Zambia's Luapula Province, has been waiting anxiously for the final test results that will decide her daughter's future. It is possible that her child may test positive for HIV. Regina's local clinic runs a prevention of mother-to-child transmission (PMTCT) program. By providing both the mother and newborn child with doses of the antiretroviral drug Neviropene, the program can reduce the chance of the virus being transmitted to the child. "During childbirth, they gave me and my baby Neviropene, and because of that I hope that my baby will be HIV-negative," said Regina.
  • Ministering through Radio and Healthcare

    White House official Jay Hein from the Office of Faith-Based and Community Initiatives attended a recent youth rally in Lusaka, Zambia. The two-day rally, called "Purity Beyond Abstinence," was sponsored by World Hope International and is part of HopeFest, a series of events that educates youth about HIV/AIDS prevention. It also focuses on living a life of purity because it "pleases God's heart." Hein was impressed by the resolve of the youth as hundreds took a stand for purity. They were also introduced to a yearlong discipleship program in southern Africa called Reach4Life aimed at preventing HIV/AIDS. HCJB Global Voice added weekly Bemba programs in 2000. The programs air on Zambia's Radio One Network, covering the country and much of Malawi, going out via shortwave, AM and FM.
  • Zambia's youth take stand for God's plan

    A White House official, Jay Hein, from the Office of Faith-Based and Community Initiatives recently attended a youth rally in Lusaka, Zambia. The rally called "Purity Beyond Abstinence" was sponsored by World Hope International, and it is about more than preventing the contraction and spread of the HIV/AIDS. It also focused on living a life of purity because it pleases God's heart. Many of those youth have likely seen the effects of HIV/AIDS all around them. Every 14 seconds, a child is orphaned because his or her parent dies from the disease.
  • The Future of PEPFAR: What Zambia Teaches Us

    Earlier this month, Population Action International (PAI) and the Sexuality Information and Education Council of the United States (SIECUS) teamed up to conduct a joint policy research trip to Zambia. Zambia is one of the 15 focus countries prioritized to receive global U.S. HIV/AIDS assistance. Zambia was also one of the first countries where PAI documented, in 2003, the destructive impact of the Global Gag Rule (also known as the Mexico City policy) on family planning and reproductive health care services. Other criteria, however, also made Zambia an ideal country through which to answer many questions about the effects of U.S. policy and funding. Long before PEFPAR's arrival, a conservative religious environment defined Zambian society, within which the promotion of abstinence and marriage were already strong currents in everyday life. First, what would the effect be after four years of the U.S. putting nearly $577 million into the country under policies that disproportionately emphasize these strategies over a more comprehensive HIV- prevention approach that included condom education and distribution? Second, how are PEPFAR policies interpreted and implemented in this environment? And have they exacerbated the dire sexual and reproductive health and rights situation in Zambia, where rural family planning and reproductive health outreach collapsed after the country's leading SRHR provider refused the terms of the Global Gag Rule? Third, has U.S. assistance harmonized with other donors and what has the Zambian government's role been in the midst of this? And finally, and perhaps most importantly, what are the needs of the health care workers on the ground and the Zambian people themselves in attempting to stem the generalized HIV epidemic in the country?
  • HIV/AIDS and treatment alongside science in Zambia

    Based on the knowledge grained from the scientists and the people with HIV/AIDS (PLWHA) about treatment of HIV/AIDS with the drug called Antiretroviral (ARV) Science has shown that people with the HIV/AIDS often become more frustrated with the management of the disease many are willing to try anything with the hope of staying healthy and living longer. What is HIV/AIDS Human immune deficiency virus (HIV) causes infections in the humans science has shown it and proofed it. It passes from one person to another through semen vaginal fluid, blood or *** milk. The most common way to get infected with HIV/AIDS is through unprotected sexual intercourse, HIV can also be transmitted(passed to another person) through injections , needles or blades that have been used on another person with HIV.Babies can get infected in the womb during birth or through the *** milk in their mother's who has the virus. The does not happen every time soothe baby of an HIV positive mother might be HIV negative with the help of the clinical trials that care on going already introduced which is Prevent of mother - to -child transmission done with the help of the drug called antiretroviral drugs. There are types in HIV, investigations have been and clinical trials where done and under taken and they showed to be two types these are HIV type one and HIV type two. At first, HIV infection does not make a person very ill. He/ she may continue to have a healthy life for some months or many years sciencfity after eight years.
  • Making a difference in Africa

    According to the World Health Organization, roughly 33.2 million people worldwide are living with HIV/AIDS. It's a staggering statistic, especially when you stop to consider that an estimated 22.5 million of those cases are concentrated in sub-Saharan Africa. When faced with such overwhelming numbers, it's tough not to feel a little daunted. But Bethany Birkelo '08 and Rachel Bean '08 didn't let that stop them. Over Interim, while hundreds of St. Olaf students ventured off the Hill for studies abroad, internships and research projects in other states or countries, Birkelo and Bean volunteered in health care centers in Livingstone, a city in the southern Zambia. Livingstone, home to roughly 100,000 people, is the adventure capital of Zambia. It's so close to Victoria Falls that you can see the mist from the city streets. As a result, it's a tourist hotspot. However, the natural beauty of the area is underscored by the fact that Livingstone has been hit hard by the AIDS epidemic.
  • US AIDS Relief program in Zambia leads to 'A Song of Hope'

    "Fortunately, I was able to start taking antiretroviral medications thanks to an AIDSRelief program in Zambia funded by the U.S. President's Emergency Plan for AIDS Relief (PEPFAR). This program is literally saving my life." LUSAKA, Zambia (CRS) - Last December on World AIDS Day, I gave President Bush a hug. I wanted to thank him and the American people who are making an incredible difference in the lives of millions living with HIV, including mine. Years ago, I wasn't doing so well. I had lost my husband to AIDS and expected to meet the same fate. My CD4 count - which measures the health of your immune system - was a mere 30 when healthy people typically have one of 500 or higher. HIV was taking its toll.
  • AIDS orphans the focus of camp ministry in Zambia

    Every Orphan's Hope runs a Bible camp outreach ministry designed to share the Gospel with the AIDS orphans of Zambia. Called Camp Hope, President Gary Schneider says it's one way to build relationships between the community and the local church. "Many times, it's five to seven churches in a local community to host a Bible camp, and over those four days, the Gospel of Christ is shared with them. They're loved on, they're cared for, fed three meals a day, provided with blankets and a Bible. It's a powerful outreach opportunity for the local churches."
  • Pres. Bush Recalls the Words of CRS Zambiaa4s Bridget Chisenga

    President Bush, in a speech this morning before leaving tomorrow for Africa with First Lady Laura Bush, made reference to a woman who made a profound impression on him: Bridget Chisenga, who works for CRS Zambia to promote adherence to antiretroviral therapy, the lifesaving medication for people living with HIV. Bridget works for AIDSRelief, the CRS-led consortium that is funded by the President's Emergency Plan for AIDS Relief (PEPFAR). Congress is currently considering legislation to reauthorize and expand PEPFAR for the next five years. "Auntie Bridget," as she is known to her co-workers and clients, spent several weeks in the fall here in the U.S. visiting schools and parishes and sharing her experiences of living with HIV and working with others with HIV. She joined President Bush for a World AIDS Day commemoration at the White House, and this morning, he recalled what she said that day:
  • Rumours of HIV in contraceptive spread panic

    A public health scare sparked by allegations that batches of the injectible contraceptive, Depro-Provera, contained the HI virus has exposed deep mistrust and high levels of misinformation about the
  • Injectable Contraceptive Depo Provera Safe

    "An invalid test was conducted by a Zambian laboratory technician recently and this led to the inaccurate rumours. The drug was designed to be tested with human blood, but this was done with somethin
  • Student starts orphanage in Zambia

    The first thing one observes about Amanda Dye is her intensity - she's driven, she's single-minded and she talks fast. But that temperament has served the William Jewell College student well.
  • Abuses Of Women Obstruct HIV Treatment

    The Zambian government is failing to address the life-threatening obstacles facing Zambian women living with HIV who experience domestic and gender-based violence, Human Rights Watch said in a report
  • Changing Hearts and Minds from the Pulpit in Zambia

    One by one, Annie Kaseketi Mwaba buried her husband and children. Then, in 2003, Annie herself fell ill. Her brother-in-law gave her permission to die. After several months, she asked her doctor
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